巴基斯坦当地人群甲状旁腺激素与高血压的关系

摘要

Mouzma Komal, Ayesha Naseem, Muhammad Usman Attaullah, Mahnoor Arshad

引言:抑郁症影响着全球3.5亿人,其终生风险为7%。到2020年,抑郁症可能会导致全球疾病负担增加5.7%,到2030年,抑郁症将成为全球残疾的主要原因。研究目的:本研究的主要目的是分析巴基斯坦当地人群中甲状旁腺激素与高血压之间的关系。研究方法:该横断面研究于2019年6月至2020年6月在拉合尔的Allama Iqbal医学院进行,获得了医院伦理委员会的许可。数据收集自200名定期到本院门诊就诊的高血压患者。所有有吸烟史的患者均被排除在本研究之外。取5ml空腹血样,分析血清钙、磷、白蛋白、甲状旁腺激素和血红蛋白。测定血清钙、磷和白蛋白。BP由一个自动ic BP监测器获得。三次测量均以坐姿休息,间隔5分钟。 The average from the last two meaIntroduction: Depression affects 350 million people around the world with a lifetime risk of 7%. Depression is likely to cause a 5.7% increase in the global burden of disease by 2020 and is to become the leading cause of disability worldwide by the year 2030. Objective of the study: The main objective of the study is to analyse the relationship between parathyroid hormone and high blood pressure among local population of Pakistan. Methodology of the study: This cross sectional study was conducted at Allama Iqbal Medical College, Lahore during June 2019 to June 2020 with the permission of ethical committee of hospital. The data was collected from 200 hypertensive patients who visited the OPD of the hospital regularly. All those patients who have the history of smoking were excluded from this study. 5 mL of fasting blood sample was taken and analysed for serum calcium, phosphorous, albumin, PTH, and haemoglobin. Serum calcium, phosphorous, and albumin were measured. BP was obtained using an automatic BP monitor. Three measures were taken at rest in a sitting position, with intervals of 5 min between the measurements. The average from the last two mea Results: The data were collected from 200 hypertensive patients. The mean age of the entire population was 45.7 ± 11.2 years. An overwhelming amount of the population was either unemployed (n=296, 72%), married (n=388, 94%), had a monthly income of less than PK Rs. 20,000, and were in the “low” category of the socioeconomic status (n=321, 78%). Amongst the educational status, most of the population had received primary or no education (n=277, 67%). Conclusion: It is concluded that underlying causes of depression need to be addressed and community programs need to be initiated to raise awareness regarding long-term complications of untreated depression, especially in hypertensive patients.

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